Irritation in the kitchen (4)
I believe the answer is:
itch
'irritation' is the definition.
(I've seen this before)
'in the kitchen' is the wordplay.
'in' indicates the answer is hidden within the clue.
'ITCH' is hidden in the letters of 'kitchen'.
(Other definitions for itch that I've seen before include "Feel tingling sensation in skin" , "It needs scratching" , "It must be scratched" , "Yen" , "Tingle" .)