Is fuming, yes, in a terrible mess! (6)
I believe the answer is:
smokes
'is fuming' is the definition.
I can't tell whether this definition defines the answer.
'yes in a terrible mess' is the wordplay.
'yes' becomes 'ok' (both are affirmative answers).
'in' means one lot of letters goes inside another.
'a terrible' is an anagram indicator.
'mess' is an anagram of 'smes'.
'ok' put within 'smes' is 'SMOKES'.
Can you help me to learn more?
(Other definitions for smokes that I've seen before include "Fumes over cigarettes" , "Products of weed" .)