Is it unhealthy to travel in one? (5)
I believe the answer is:
wagon
'is it' is the definition.
I can't judge whether this definition defines the answer.
'unhealthy to travel in one?' is the wordplay.
'unhealthy' becomes 'w' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'to travel' becomes 'go' (synonyms).
'in' means one lot of letters goes inside another.
'one?' becomes 'an' (an apple is one apple).
'go' going inside 'an' is 'agon'.
'w'+'agon'='WAGON'
Can you help me to learn more?
(Other definitions for wagon that I've seen before include "Wheeled vehicle drawn by a horse" , "Vehicle (on which abstainers travel?)" , "Cart; rail truck" , "Railway freight vehicle" , "Wild West trail vehicle?" .)