Is set to change places (5)
I believe the answer is:
sites
'places' is the definition.
(a site is a place or location)
'is set to change' is the wordplay.
'to change' is an anagram indicator.
'is'+'set'='isset'
'isset' with letters rearranged gives 'SITES'.
(Other definitions for sites that I've seen before include "Is set among building locations" , "Spots" , "Is set (anag)" , "Locates" , "Locations or positions, as for building" .)