Is upset by good quality autograph (9)
I believe the answer is:
signature
'autograph' is the definition.
(I've seen this before)
'is upset by good quality' is the wordplay.
'upset by' is an anagram indicator.
'good' becomes 'g' (abbreviation).
'quality' becomes 'nature' (nature is a kind of quality).
'is' with letters rearranged gives 'si'.
'si'+'g'+'nature'='SIGNATURE'
(Other definitions for signature that I've seen before include "Distinctive way of writing name" , "X-WORD ?" , "Distinctive characteristic" , "Identifying piece of writing, tune etc" , "ending to letter?" .)