Isaac of sci-fi (6)
I believe the answer is:
asimov
'isaac of sci-fi' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for asimov that I've seen before include "novelist" , "Isaac ---, SF author" , "Isaac --, sci-fi author" , "Isaac --, science fiction author" , "See 22 Down" .)