Isaac’s son second to visit Arab lands to the west (4)
I believe the answer is:
esau
'isaac's son' is the definition.
(son of Isaac in the Bible)
'second to visit arab lands to the west' is the wordplay.
'second' becomes 's' (common abbreviation).
'to visit' indicates putting letters inside (inserted letters visit others).
'arab lands' becomes 'uae' (I can't justify this - if you can you should believe this answer much more).
'to the west' shows that the letters should be reversed in order (letters written right to left or 'east to west').
's' placed within 'uae' is 'uase'.
'uase' backwards is 'ESAU'.
Can you help me to learn more?
(Other definitions for esau that I've seen before include "wronged brother" , "Hairy brother to Jacob in Bible" , "Jacob's brother (OT)" , "Old Testament character sounds as if he had a vision" , "Elder of the twin sons of Isaac and Rebecca" .)