Island south of Sicily (5)
I believe the answer is:
malta
'island south of sicily' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for malta that I've seen before include "Mediterranean island, capital Valletta" , "defiant island in WW2" , "seagirt republic" , "The capital is Valetta" , "Island nation" .)