Israelite’s manly drink? (6)
I believe the answer is:
hebrew
'israelite's' is the definition.
'manly drink?' is the wordplay.
'manly' becomes 'he' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'drink?' becomes 'brew' (brew is a kind of drink).
'he'+'brew'='HEBREW'
(Other definitions for hebrew that I've seen before include "Middle Eastern language" , "Tongue" , "One claiming descent from Abraham" , "Israel's official language" , "could be Isaac" .)