It can mean "modified" (3)
I believe the answer is:
neo
'it can mean modified' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for neo that I've seen before include "Prefix meaning new - try one" , "Prefix meaning new or recent" , "language" , "Hero of The Matrix films; new (prefix)" , "Prefix meaning new, maybe one" .)