It can, of course, spoil satin (5)
I believe the answer is:
stain
'it can of course' is the definition.
The definition suggests a singular noun which matches the answer.
'spoil satin' is the wordplay.
'spoil' indicates an anagram.
'satin' with letters rearranged gives 'STAIN'.
Can you help me to learn more?
(Other definitions for stain that I've seen before include "Smear" , "Blot" , "Discolour - blemish" , "Unsightly mark" , "Stigma" .)