Crossword Genius

It may be smoked out of its den (5)

Ross

I believe the answer is:

opium

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This might be a double definition.

'it may be smoked out of its' is the first definition.
The definition suggests a singular noun which matches the answer.

'den' is the second definition.
The definition and answer can be both man-made objects as well as being singular nouns.
Maybe you can see an association between them that I don't see?

Can you help me to learn more?

(Other definitions for opium that I've seen before include "Derivative of Poppy" , "Poppy-based drug" , "wars with China" , "The stuff of wars" , "justification for war once?" .)

I've seen this clue in The Globe and Mail.
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