It may be used when charming women turned up make-up (4)
I believe the answer is:
wand
'it may be used when charming' is the definition.
The definition suggests a singular noun which matches the answer.
'women turned up make-up' is the wordplay.
'women' becomes 'w' (standard abbreviation).
'turned up' is a reversal indicator.
'make-up' becomes 'DNA' (a person's genetic make-up).
'dna' in reverse letter order is 'and'.
'w'+'and'='WAND'
Can you help me to learn more?
(Other definitions for wand that I've seen before include "Extremely angry" , "Rod of magician or water-diviner" , "spelling aid" , "Magician's rod" , "Magical rod" .)