It means a lot to many a fathead (4)

I believe the answer is:

mass

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'it means a lot' is the definition.
The definition suggests a singular noun which matches the answer.

'many a fathead' is the wordplay.
'many' becomes 'm' (Roman numeral for a thousand).
'a fathead' becomes 'ass' (I've seen this in another clue).
'm'+'ass'='MASS'

'to' acts as a link.

Can you help me to learn more?

(Other definitions for mass that I've seen before include "Widespread" , "Roman Catholic service" , "Religious rite" , "Body of matter" , "Throng" .)

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