It unfits men for high positions (7)

I believe the answer is:

vertigo

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'it unfits men for high positions' is the definition.
The definition suggests a singular noun which matches the answer.

This is all the clue.

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(Other definitions for vertigo that I've seen before include "Disturbance in the inner ear" , "attack at altitude?" , "Sense of dizziness - Hitchcock film" , "Sensitivity to heights" , "Whirling sensation when balance is disturbed" .)

I've seen this clue in The Globe and Mail.

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