Italian article accepted by Red Cross (5)
I believe the answer is:
riled
'cross' is the definition.
(I've seen this before)
'italian article accepted by red' is the wordplay.
'italian article' becomes 'il' (the definite article in Italian).
'accepted by' means one lot of letters goes inside another (inserted letters are accepted).
'il' inserted into 'red' is 'RILED'.
(Other definitions for riled that I've seen before include "Cross" , "get angry" , "Nettled" , "Annoyed" , "Made angry" .)