Italian city, home to La Scala (5)
I believe the answer is:
milan
I believe this is a double definition.
'italian city' is the first definition.
(city in Italy)
'home to la scala' is the second definition.
(I've seen this in another clue)
(Other definitions for milan that I've seen before include "town" , "Italian industrial city" , "Northern Italian city" , "North Italian city" , "Capital of Lombardy" .)