Italian spirit (6)
I believe the answer is:
grappa
'italian spirit' is the definition.
(I've seen this before)
This is all the clue.
(Other definitions for grappa that I've seen before include "Spirit distilled from grapes" , "Italian brandy distilled from grape lees" , "Brandy from fermented pressed grape residue" , "Type of brandy" , "Italian spirit made from grape residue after pressing" .)