Itches to change moral values (6)
I believe the answer is:
ethics
'moral values' is the definition.
(I've seen this in another clue)
'itches to change' is the wordplay.
'to change' indicates anagramming the letters.
'itches' with letters rearranged gives 'ETHICS'.
(Other definitions for ethics that I've seen before include "Moral principles in middle" , "body of principles" , "Codes of standards in business" , "Code of behaviour" , "Work of Aristotle" .)