Item inherited from Guernsey regularly (4)
I believe the answer is:
gene
'item inherited from' is the definition.
I can't judge whether this definition defines the answer.
'guernsey regularly' is the wordplay.
'regularly' indicates alternate letters (regularly take one letter, leave next etc.).
The alternating letters of 'guernsey' are 'GENE'.
Can you help me to learn more?
(Other definitions for gene that I've seen before include "What makes us different" , "___ Kelly, star of Singin' In The Rain, d. 1996" , "A segment of DNA" , "Hereditary DNA sequence" , "Something got from parent < for boy" .)