It's applied with experience (4)
I believe the answer is:
used
'it's applied' is the definition.
('use' can be a synonym of 'apply')
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for used that I've seen before include "Employed in task, or second-hand" , "taken advantage of!" , "not got directly" , "worked unfairly" , "was milking" .)