It's beneficial so long as profit prioritised (10)
I believe the answer is:
worthwhile
'prioritised' is the definition.
The answer and definition are different parts of speech. However, past participle verbs and adjectives can occasionally mean the same thing.
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for worthwhile that I've seen before include "Justified in terms of time spent" , "Of use" , "Useful and rewarding" , "Justifying the time spent on it" .)