It's clear dope's seized by copper? Quite the reverse (2,5)
I believe the answer is:
in focus
'it's clear' is the definition.
(as in a camera)
'dope's seized by copper? quite the reverse' is the wordplay.
I cannot quite understand how this works, but
'copper?' could be 'cu' (chemical symbol) and 'cu' is located in the answer.
'dope's' could be 'infos' (dope can informally mean information) and 'infos' is found within the remaining letters.
No letters remain.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for in focus that I've seen before include "Not blurred" , "Clear" , "Clearly defined" .)