It's disconcerting playing tiring Dubs (10)
I believe the answer is:
disturbing
'it's disconcerting' is the definition.
(thesaurus)
'playing tiring dubs' is the wordplay.
'playing' is an anagram indicator.
'tiring'+'dubs'='tiringdubs'
'tiringdubs' anagrammed gives 'DISTURBING'.
(Other definitions for disturbing that I've seen before include "Upsetting" , "doing shiftwork?" , "Scary" , "Worrying" .)