It's funny about cleaner's endless prejudice ... such as this? (10)
I believe the answer is:
homophobia
'as this?' is the definition.
The definition suggests a singular noun which matches the answer.
'it's funny about cleaner's endless prejudice' is the wordplay.
'it's funny' becomes 'hoho' (I can't justify this - if you can you should give a lot more credence to this answer).
'about' indicates putting letters inside.
'cleaner' becomes 'mop' (something which 'cleans').
'endless' means to remove the last letter.
'prejudice' becomes 'bias' (biasing is a kind of prejudicing).
'hoho' placed around 'mop' is 'homopho'.
'bias' with its last letter taken away is 'bia'.
'homopho'+'bia'='HOMOPHOBIA'
'such' is the link.
Can you help me to learn more?