It’s shrewd to get out of the way thus (6)
I believe the answer is:
wisely
'thus' is the definition.
Both the answer and definition are adverbs. Perhaps they are linked in a way I don't understand?
'it's shrewd to get out of the way' is the wordplay.
'it's shrewd' becomes 'wily' (I've seen this before).
'to get' is an insertion indicator.
'out of the way' becomes 'se' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'wily' placed around 'se' is 'WISELY'.
Can you help me to learn more?
(Other definitions for wisely that I've seen before include "Carefully considered, sagely" , "Sensibly" , "Judiciously" , "With intelligence" , "how Solomon acted" .)