It's sweet taking drugs in Hungary on vacation (5)
I believe the answer is:
honey
'it's sweet' is the definition.
(thesaurus)
'taking drugs in hungary on vacation' is the wordplay.
'taking' becomes 'on' (eg one taking drugs is 'on' drugs).
'drugs' becomes 'E' (E can mean ecstasy).
'in' is an insertion indicator.
'on vacation' means to remove the middle letters (after the inside letters have vacated the word).
'hungary' with its centre removed is 'hy'.
'on'+'e'='one'
'one' inserted inside 'hy' is 'HONEY'.
(Other definitions for honey that I've seen before include "Substance made by bees" , "Sweet food" , "sweetheart" , "Treasure" , "Hive's product" .)