It's working in shift that causes grief (8)
I believe the answer is:
distress
'causes grief' is the definition.
'distress' can be an answer for 'grief' (I've seen this before). I'm unsure of the 'causes' bit.
'it's working in shift' is the wordplay.
'working' indicates anagramming the letters.
'in' is an insertion indicator.
'shift' becomes 'dress' (shift can mean a dress).
'its' with letters rearranged gives 'ist'.
'ist' inserted into 'dress' is 'DISTRESS'.
'that' is the link.
Can you help me to learn more?
(Other definitions for distress that I've seen before include "Anguish - trouble - danger" , "A strong feeling of anxiety or suffering 98)" , "Extreme anxiety or pain" , "State of anxiety or woe" , "Such a signal indicates trouble" .)