It's wrong Susan! In the paper! (6)
I believe the answer is:
tissue
'paper' is the definition.
(tissue paper is a kind of paper)
'it's wrong susan' is the wordplay.
'wrong' indicates an anagram.
'susan' becomes 'sue' (short for Susan).
'its' anagrammed gives 'tis'.
'tis'+'sue'='TISSUE'
'in the' acts as a link.
(Other definitions for tissue that I've seen before include "See 17" , "cell block?" , "Thin paper; concoction (of lies)" , "Maybe lies" , "Basic structural element of an animal or plant" .)