Jelly may be a special interest choice initially (5)
I believe the answer is:
aspic
'jelly' is the definition.
(I know that aspic is a type of jelly)
'a special interest choice initially' is the wordplay.
'special' becomes 'sp' (abbreviation).
'initially' indicates taking the first letters.
The initial letters of 'interest choice' is 'ic'.
'a'+'sp'+'ic'='ASPIC'
'may be' is the link.
(Other definitions for aspic that I've seen before include "Savoury jelly for coating meat, eggs etc" , "Jelly based on fish or meat stock" , "Setter" , "Ending of Marlowe's thriller" , "Clear savoury jelly" .)