Joint from an animal brought up (5)
I believe the answer is:
ankle
'joint' is the definition.
(joint of the body)
'an animal brought up' is the wordplay.
'animal' becomes 'elk' (I have seen 'American animal ' mean 'elk' so perhaps 'animal' could also mean 'elk').
'brought up' shows that the letters should be reversed in order (in a down clue, letters go up).
'elk' backwards is 'kle'.
'an'+'kle'='ANKLE'
'from' is the link.
(Other definitions for ankle that I've seen before include "Joint between foot and leg" , "Part of the leg between the foot and the shin" , "Lower leg joint" , "Human joint" , "Bone over foot" .)