Jolt from significant remorse (6)
I believe the answer is:
tremor
'jolt' is the definition.
(thesaurus)
'from significant remorse' is the wordplay.
'from' says the answer is hidden in the clue.
'TREMOR' can be found hidden inside 'significant remorse'.
(Other definitions for tremor that I've seen before include "Nervousness" , "Small shock" , "Minor quake" , "Bit of excitement" , "Small vibration" .)