Judge a female beast of burden? (6)
I believe the answer is:
assess
'judge a female' is the definition.
'assess' can be an answer for 'judge' (to assess is to judge or rate). I am not sure about the 'a female' bit.
'beast of burden?' is the wordplay.
'beast' becomes 'ass' (donkey).
'of burden?' becomes 'ess' (I can't explain this - if you can you should believe this answer much more).
'ass'+'ess'='ASSESS'
Can you help me to learn more?
(Other definitions for assess that I've seen before include "Estimate, gauge" , "Remedy for all ills" , "Fix the amount of tax" , "price" , "'Judge, estimate (6)'" .)