Kansai location huge — there's another name for it (5)
I believe the answer is:
osaka
'kansai location' is the definition.
(city in Kansai)
'huge there's another name for it' is the wordplay.
'huge' becomes 'os' (abbreviation for outsize).
'there's another name for it' becomes 'aka' (also known as).
'os'+'aka'='OSAKA'
(Other definitions for osaka that I've seen before include "Far East city" , "Place" , "Third largest city in Japan" , "Asian" , "Third most populous Japanese city" .)