"___ Karenina" (novel with the line, "If you look for perfection, you'll never be content") (4)
I believe the answer is:
anna
(Other definitions for anna that I've seen before include "Dame -- Neagle" , "-- Karenina, Tolstoy novel" , "Unit of length" , "Book by Tolstoy" , "- - Ford (TV)" .)