Keanu's "The Matrix" role (3)
I believe the answer is:
neo
'keanu's the matrix role' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for neo that I've seen before include "Prefix meaning new, maybe one" , "Prefix donating new" , "Prefix meaning new of modern form of" , "New (suffix)" , "Prefix meaning new or recent" .)