Keen political faction suppressing misfortune (7)
I believe the answer is:
willing
'keen' is the definition.
(keen can mean willing or enthusiastic)
'political faction suppressing misfortune' is the wordplay.
'political faction' becomes 'wing' (left or right wing).
'suppressing' indicates putting letters inside.
'misfortune' becomes 'ill' (ill is a kind of misfortune).
'wing' enclosing 'ill' is 'WILLING'.
(Other definitions for willing that I've seen before include "Compliant" , "prepared" , "game?" , "Ready and eager" , "Amenable, consenting" .)