Key meetings are disrupted by conflict (12)
I believe the answer is:
disagreement
'conflict' is the definition.
(disagreement is a kind of conflict)
'key meetings are disrupted' is the wordplay.
'key' becomes 'd' (I've seen this in other clues**).
'disrupted' is an anagram indicator.
'meetings'+'are'='meetingsare'
'meetingsare' with letters rearranged gives 'isagreement'.
'd'+'isagreement'='DISAGREEMENT'
'by' is the link.
(Other definitions for disagreement that I've seen before include "dispute" , "Argument" , "Contretemps" , "Difference of opinion" , "Conflict" .)