Key trophy picked up for initiative (10)
I believe the answer is:
enterprise
'initiative' is the definition.
(synonyms)
'key trophy picked up' is the wordplay.
'key' becomes 'enter' (key on a computer keyboard).
'trophy' becomes 'prize' (synonyms).
'picked up' shows a homophone (sound like).
'prize' is a homophone of 'prise'.
'enter'+'prise'='ENTERPRISE'
'for' acts as a link.
(Other definitions for enterprise that I've seen before include "Initiative - undertaking - business" , "audacity" , "Project, undertaking" , "Get-up-and-go - venture" , "Company" .)