Know boy brought up in town (6)
I believe the answer is:
kendal
'town' is the definition.
(English town)
'know boy brought up' is the wordplay.
'know' becomes 'ken' (Scottish term meaning to know).
'boy' becomes 'lad' (informal term for boy).
'brought up' says the letters should be written backwards (in a down clue, letters go up).
'lad' backwards is 'dal'.
'ken'+'dal'='KENDAL'
'in' is the link.
(Other definitions for kendal that I've seen before include "Cumbrian town; green cloth name" , "Town in Cumbria" , "Cumbrian town - gateway to the Lake District" , "Lakeland town known for mint cake" .)