Knowledge about one river (5)
I believe the answer is:
loire
'one river' is the definition.
(Loire River is an example)
'knowledge about' is the wordplay.
'knowledge' becomes 'loi' (I can't explain this - if you can you should give a lot more credence to this answer).
'about' becomes 're' ('re' means regarding or about).
'loi'+'re'='LOIRE'
Can you help me to learn more?
(Other definitions for loire that I've seen before include "French department" , "flower abroad" , "Longest French river" , "French runner" , "Current French" .)