Knows main female relation (9)
I believe the answer is:
kinswoman
'relation' is the definition.
(I know that kinswoman is a type of relation)
'knows main female' is the wordplay.
'knows main' can be anagrammed to 'KINSWOMAN'.
Though, I am not sure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for kinswoman that I've seen before include "Female relative" , "one of the family!" , "Female family member" , "Relation" .)