LA guys wanting English clothes (4)
I believe the answer is:
duds
'clothes' is the definition.
(duds is a kind of clothes)
'la guys wanting english' is the wordplay.
'la guys' becomes 'dudes' (US term for guys or men, eg in LA).
'wanting' suggests deleting specific letters (to want something can mean to lack it or need it).
'english' becomes 'e' (abbreviation).
'dudes' with 'e' taken away is 'DUDS'.
(Other definitions for duds that I've seen before include "Failures; clothes" , "Bombs that fail to explode" , "One assumes them" .)