Lack of reaction to the negative answer (2,8)

'lack' is the definition.
I know nothing about this answer so I can't tell whether it can be defined by this definition.

'reaction to the negative answer' is the wordplay.
'reaction' becomes 'response' (synonyms).
'to' means one lot of letters go next to another (I've seen this in other clues).
'the negative answer' becomes 'no'.
'response' put after 'no' is 'NO RESPONSE'.

'of' acts as a link.

Can you help me to learn more?