Lacking experience, one's thrown out of everything and departs (8)
I believe the answer is:
unversed
'lacking experience' is the definition.
'one's thrown out of everything and departs' is the wordplay.
'one' becomes 'i' (Roman numeral).
'thrown out of' suggests deleting specific letters.
'everything' becomes 'universe' (I've seen this before).
'and' says to put letters next to each other.
'departs' becomes 'd' (common abbreviation e.g. train timetables).
'universe' with 'i' taken out is 'unverse'.
'unverse'+'d'='UNVERSED'
(Other definitions for unversed that I've seen before include "Not experienced or skilled" , "Not in rhyme" , "Green" , "Lacking skill" .)