Ladies perhaps hide, forgoing second chance (4-2)
I believe the answer is:
look-in
'chance' is the definition.
(I've seen this before)
'ladies perhaps hide forgoing second' is the wordplay.
'ladies perhaps' becomes 'loo' (I've seen this in other clues).
'hide forgoing second' becomes 'kin' (I can't explain this - if you can you should give a lot more credence to this answer).
'loo'+'kin'='LOOK-IN'
Can you help me to learn more?
(Other definitions for look-in that I've seen before include "Watch TV (colloq.)" , "Chance of success" , "Make a short visit of visual sort?" .)