Large country house (5)
(Other definitions for manor that I've seen before include "Large country house for Roman" , "lord's home" , "Operational base" , "Grand but strange Roman house" , "Lord's estate" .)
'large country house' is the definition.
(I've seen this before)
This is all the clue.
(Other definitions for villa that I've seen before include "Roman domicile" , "Ancient Roman's country house" , "See 3" , "Holiday residence" , "Ancient Roman country house" .)