Crossword Genius

Large dress designed anyhow (10)

Ross

I believe the answer is:

regardless

'anyhow' is the definition.
(thesaurus)

'large dress designed' is the wordplay.
'designed' is an anagram indicator (designed with the letters).
'large'+'dress'='largedress'
'largedress' anagrammed gives 'REGARDLESS'.

(Other definitions for regardless that I've seen before include "Despite the prevailing circumstances" , "in any case" , "in spite of everything" , "Anyway" , "CARRY ON FILM" .)

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