Crossword Genius

Large four-stringed instrument (5)

Ross

I believe the answer is:

cello

(Other definitions for cello that I've seen before include "Jacqueline du Pre's instrument" , "Bass stringed instrument" , "Lloyd Webber's instrument" , "Orchestral instrument played between the legs" , "music produced by this?" .)

I've seen this clue in the Sydney Morning Herald.
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