Large port? That'll get you loaded! (5)
I believe the answer is:
laden
'loaded' is the definition.
(synonyms)
'large port?' is the wordplay.
'large' becomes 'L' (eg in clothes sizes).
'port?' becomes 'aden' (port in Yemen).
'l'+'aden'='LADEN'
'that'll get you' is the link.
I am not very happy about this link. Some or all of it may belong to another bit of the clue.
Can you help me to learn more?
(Other definitions for laden that I've seen before include "Eland (anag)" , "Carrying goods" , "Of ship, having taken on cargo" , "Heavily weighed down" , "bearing burden" .)